The Englishmen wanted to have of it the net heart and here is which is made: the programme of speeded up vaccination which they adopted in 1990 is not linked to the unexpected sudden death of the new-born baby, that it is explained or unexplained. IL would have there even an inverse tendency. The age to whom the children accept their first vaccinations corresponding to the peak of age of the cot death; what led to speculate about a relation between two.

These twenty last years, insulated observations and some studies case controls suggested a possible association. But series of studies arrived at opposite conclusion and one of her even suggested as the programme of vaccination speeded up contributes to a reduction among dead sudden. But all these studies included biases.

In 1990, the programme of vaccination was speeded up in the United Kingdom: first vaccines against diphtheria, tetanus, whooping cough and poliomyelitis are managed now in 2, 3 and 4 months instead of 3, 5 and 9 months; since 1992, the vaccine against Haemophilus in.fluenzae of type b is also linked.
A job on 470 000 births

A British team undertook a big study case controls on the unexpected death of the new-born baby after the sudden installation of the programme of vaccination speeded up and the reduction of the rate of dead noticed at the beginning of 1990s. This job, which lasted three years (from February, 1993 till March, 1996), concerned the dead babies suddenly between 1 week and 1 year, within a population of 17,7 million persons. For every died child, four controls were chosen. They established one period  reference of sleep  corresponding at the time when case index had died. They gathered (by a form changed of Cambridge Baby Check) the signs of illness of case index and controls in twenty-four hours preceding decease or reference period.
More vaccinating to controls

A child was considered as vaccinated if he had already accepted at least one of the vaccines. On more than 470 000 births, there was 456 dead sudden unexpected, among whom 363 dead sudden unexplained, and 93 dead sudden unexpected but explained.

Among the children having had an unexplained sudden death, a little less half had been vaccinated, against two thirds of controls. Vaccination appears therefore to first access strongly linked to a reduction of the risk of unexplained sudden death (odds ratio: 0,45). However, after recognition of some factors (child put to bed on the belly, clothes covering the head, for example), difference becomes not significant (0,67; from 0,31 to 1,43).

The average of age during the first vaccine was of 61 days for unexplained death and of 59 days at the babies controls. Delays between last vaccine and unexplained death or period of sleep were of 27 and 29 days; finally, 5 % of dead babies had accepted a vaccine in 48 hours preceding decease and 5 % controls before the reference period. For dead explained, 6 % died in 48 hours according to vaccine (3 % controls for the reference period).

In total, more than third parties of the dead sudden unexplained happened between 2 and 4 months, ages of vaccinations. So that it is more than of a coincidence, the vaccinal cover would have to be superior at the dead children's that to controls. And yet it is the opposite which was determined.  Our data suggest that vaccination does not contribute at the risk of sudden death and can protect against her  , estimate the authors.  We conclude that the programme of vaccination speeded up in the United Kingdom is not linked to unexpected sudden death, that it is explained or unexplained  , they conclude.

Dr E.deV., the daily of the doctor, 4/9/2001 Peter Fleming and colL (Bristol board). "BMJ" of April 7th, 2001, pp. 822-825.